Fresh off his maiden triple win at Donington Park a fortnight ago, Razgatlioglu clocked 1m31.506s in the closing stages of the afternoon session to grab the lead, beating the Jonathan Rea’s FP1 benchmark by almost four tenths of a second.
BMW’s Scott Redding briefly topped the timesheets with a 1m32.081s and managed to gain another four tenths in the final 10 minutes, but eventually had to settle for second, 0.227s off Razgatlioglu’s fastest time.
Third and fourth place went to Ducati, with Michael Ruben Rinaldi edging championship-leading teammate Alvaro Bautista by just 0.051s with a best effort of 1m31.820s.
Rinaldi remained top of the leaderboard for much of the 45-minute practice but was dethroned by Redding, before Razgatlioglu grabbed the lead and sent the Italian into third place.
Loris Baz was the best satellite rider on the Bonovo MGM BMW in fifth place with a time of 1m32.039s, validating the upgrade the German manufacturer made its Donington debut in its quest to move up the pecking order.
Rea finished sixth with an identical lap to Baz, his Kawasaki teammate Alex Lowes doing no better in eighth.
After dominating the opening practice earlier on Friday, Rea appeared to focus on long runs later in the afternoon and rarely featured near the top of the order.
Separating the two Kawasaki bikes, Andrea Locatelli’s second works Yamaha was seventh, while the top 10 was completed by Xavi Vierge on the works Honda and Garrett Gerloff on the GRT Yamaha.
Virgin’s teammate Iker Lecuona crashed on just his third lap out of the pits and did not return to the track afterwards, his only flying lap leaving him 16th on the timesheets. The former MotoGP rider had previously finished in the top 10 in an uneventful FP1.
Most marked the return of Isle of Man TT winner Peter Hickman to a factory BMW bike after his wildcard outing with FHO Racing at his home event earlier this month.
Replacing injured Michael van der Mark on a bike ridden in recent races by Ilya Mikhalchik, Hickman finished 21st and 22nd respectively in the two sessions with a best effort of 1m34.125s.